Dementia in the Oldest Old

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Dementia in the oldest old.

PURPOSE OF REVIEW This article discusses some of the unique features of dementia in the oldest old, including some of the most common diagnostic challenges, and potential strategies to overcome them. RECENT FINDINGS Advances include new insight into the role of common risk factors and the effects of multiple underlying neuropathologic features for dementia in the oldest old. In addition, this...

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Challenges of diagnosing dementia in the oldest old population.

People aged 90 and older are the fastest growing age group in most parts of the world. Since the prevalence of dementia has been shown to increase exponentially after the age of 65, there is an acceptance that the oldest old population has a high burden of dementia; however, there is a lack of consensus on how best to diagnose dementia in this population. This review summarizes the various appr...

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Dementia in the oldest old: Beyond Alzheimer disease

In a Perspective, Aimee Pierce and Claudia Kawas discuss risk factors and pathologies of dementia in the oldest-old.

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Cognitive Decline and Dementia in the Oldest-Old

The oldest-old are the fastest growing segment of the Western population. Over half of the oldest-old will have dementia, but the etiology is yet unknown. Age is the only risk factor consistently associated with dementia in the oldest-old. Many of the risk and protective factors for dementia in the young elderly, such as ApoE genotype, physical activity, and healthy lifestyle, are not relevant ...

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Role of the neuropathology of Alzheimer disease in dementia in the oldest-old.

BACKGROUND Neuritic plaques (NPs) and neurofibrillary tangles (NFTs) in the brain, especially in the hippocampus, entorhinal cortex, and isocortex, are hallmark lesions of Alzheimer disease and dementia in the elderly. However, this association has not been extensively studied in the rapidly growing population of the very old. OBJECTIVE To assess the relationship between estimates of cognitiv...

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ژورنال

عنوان ژورنال: CONTINUUM: Lifelong Learning in Neurology

سال: 2013

ISSN: 1080-2371

DOI: 10.1212/01.con.0000429172.27815.3f